Labels:text | screenshot | black and white | black | font | document OCR: Pierre Acromegaly was first described in 1886 tal Marie, who noted 'a striking nonconge the face, hypertrophy of the extremities' includi that this hands and feet. In 1891 Minkowski not hypertrophy was always accompanied 894 enlarged pituitary, which Tamburine i recognised as a pituitary adenoma. the first to However, Harvey Cushing, in 1909, wa e the use the word 'hypopituitarism' to desc Evans, jection of condition. This was confirmed in 1922 who demonstrated that the parenteral ry gland extracts of the anterior lobe of the pitui hyses in dogs, causes true gigantism in rats, whose ep never fuse, and acromegalic-like featur whose epiphyses do.
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